Regaine aerosol for outside. apply. 5% balloon 60 ml # 1

Solution for external use

Packaging

Bottle 60 ml

pharmachologic effect

Pharmacodynamics

With topical application of minoxidil, its stimulating effect on hair growth in persons with androgenetic alopecia (thinning hair, baldness) was noted.

The appearance of signs of hair growth is noted after 4 or more months of using the drug 2 times a day.

The onset and severity of the effect may vary from patient to patient.

After stopping the use of REGINE, the growth of new hair stops, and within 3-4 months it is possible to restore the original appearance.

The exact mechanism of action of REGINE in the treatment of androgenetic alopecia is unknown.

In controlled clinical trials, after topical application of REGINE, both in patients with normal and in patients with high blood pressure, no systemic side effects associated with the absorption of minoxidil were observed.

Pharmacokinetics

When applied externally, minoxidil is poorly absorbed through normal, intact skin: on average, 1.4% (0.3 - 4.5%) of the total applied dose enters the systemic circulation.

When 1 ml of REGAIN is applied to the skin, 5% solution for external use, which corresponds to 50 mg of minoxidil, 0.70 mg of minoxidil is absorbed.

When applied externally, the serum level of minoxidil is determined by the rate of its absorption through the skin.

After discontinuation of the drug, approximately 95% of minoxidil that has entered the systemic circulation is excreted within 4 days.

Indications

Androgenetic alopecia in men and women (in order to restore the hairline or stabilize the hair loss process).

Contraindications

- children and adolescents up to 18 years old

- hypersensitivity to minoxidil and other components of the drug.

The drug should not be applied in case of redness, inflammation, infection, soreness of the scalp (including sunburn).

Application during pregnancy and lactation

Regaine should not be used during pregnancy and lactation.

special instructions

In addition to hereditary predisposition, hair loss can be caused by other factors: Regaine does not prevent hair loss caused by certain drugs, nutritional disorders (iron or vitamin A deficiency in the body), and hair loss due to tight hairstyles.

The patient should be warned about the need to consult a doctor in cases where hair loss began suddenly, baldness is focal in nature and the patient has a pathology from the cardiovascular system.

If systemic side effects appear (chest pains, palpitations, dizziness, decreased blood pressure, sudden weight gain, swelling of the arms and / or legs), as well as redness and irritation at the site of rubbing, the drug should be discontinued and, if necessary, appropriate therapy should be prescribed.

In case of contact with eyes, damaged skin or mucous membranes, immediately rinse the affected area with plenty of running cold water.

Inhalation of the drug when spraying should be avoided.

In some patients, after using the drug, a change in the color and structure of the hair was observed.

Avoid rinsing the drug, hair can be wetted no earlier than 4 hours after applying Regain.

During the period of application of Regain, you can use hair care products (including hairspray).

In this case, you should first apply the drug and let the treated skin area dry completely, and then apply care products.

Currently available data show that dyeing hair, perming or using conditioners does not reduce the effectiveness of Regaine, provided that the preparation is completely washed off the hair and scalp prior to these procedures.

Structure

1 ml of solution contains:

Active substance: mino

Name ENG

REGAINE

ATX code

Minoxidil

Dosage

5% x 60ml

Structure

1 ml of solution contains: Active substance: minoxidil 50 mg

Excipients: ethanol, propylene glycol, purified water.

Indications

Androgenetic alopecia in men and women (in order to restore the hairline or stabilize the hair loss process).

INN / Active ingredient

minoxidil

Storage conditions and periods

At a temperature not higher than 25 degrees.

Expiration date: 3 years

Contraindications

Children and adolescents up to 18 years old

hypersensitivity to minoxidil and other components of the drug.

The drug should not be applied in case of redness, inflammation, infection, soreness of the scalp (including sunburn).

Specifications

Category

Baldness

Scope of the medicinal product

Leather

Release form

Spray

Manufacturer country

Switzerland

Package quantity, pcs

one

Way of introduction

On the skin

Vacation conditions

Without recipe

Brand name

Regaine

Components

spray nozzle, spray bottle

The amount of the dosage form in the primary package

60 ml

Primary packaging type

Bottle

Type of consumer packaging

Pack of cardboard

Pharmaco-therapeutic group

Alopecia Remedy

Anatomical and therapeutic characteristics

D11AX01 Minoxidil [Topical]

Dosage form

Solution for external use

Dosage (volume) of the substance in the preparation

50 mg

Expiration date in days

1095

Package weight, g

135

Mode of application

:

For external use only.

Use REGAIN only as directed.

Do not apply REGAIN to other areas of the body.

< br> REGAIN in a dose of 1 ml is applied 2 times a day (morning and evening) on ��the scalp, starting from the center of the affected area and around the affected area.

This dose is independent of the size of the affected area.

The total daily dose should not exceed 2 ml.

Wash your hands thoroughly after applying REGAIN.

Apply REGAIN only to the scalp, after drying your hair well.

One bottle of REGAIN is designed to be used for 30 days.

< br> To maintain a stable effect, constant use of the drug is recommended.

Information on technical characteristics, delivery set, country of manufacture